The Central Fire Station received an alarm from the premises shortly after 11:30 p.m. Thursday.
Fire was showing on the first floor when firefighters arrived, District Fire Chief Adam Roach said at the scene.
Roach said fire was confined in one room and was put out in 10 minutes.
The sprinkler system was activated and help prevent the fire from spreading, Roach said.
A second alarm was sounded for precautionary reasons, according to Roach.
A historic property, the Bull Mansion was built in 1876 as a home. It was later used as a post of the Civil War veterans’ organization Grand Army of the Republic, and in more recent years has been used for dining and entertainment, including the popular “Haunted Speakeasy” series hosted by Niki Luparelli.