Crews with the Winnipeg Fire Paramedic Service were called to the fire at a five-storey building in the 100 block of Creek Bend Road just after 1:40 a.m.
When firefighters got to the scene, they found smoke and flames coming from the building.
The city noted the sprinkler system was activated, and crews extinguished the fire just after 2:20 a.m.
Paramedics treated one person at the scene, but they did not have to go to the hospital. The evacuated residents used Winnipeg Transit buses as temporary shelters.