Crews responded around 10 a.m. to the AmericInn at 1031 S. Diamond Circle for a structure fire, said Todd Lowe, the incident commander for the Hartford Fire Department. The Hartford Fire Department was assisted by eight other agencies, including Tea, Humboldt, Colton and Sioux Falls Fire Rescue.
While a sprinkler system helped contain the fire, everyone was evacuated from the building by the time agencies responded.
The fire was contained to the third floor, which sustained fire and smoke damage.
The state fire marshal is responding to the incident and investigating the cause of the fire. Lowe did not release where the fire started.
Authorities do not have an estimate on the total amount of damage to the hotel yet.